Fluorinated 4H-1,3-Diazepines by Reaction of Difluorocarbene with 2H-Azirines.
β Scribed by Mikhail S. Novikov; Amer A. Amer; Alexander F. Khlebnikov
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Reaction of 2,2-dialkyl-3-(dimethylamino)-2H-azirines la and l b with 2.3-pyridinedicarboximide (4) in MeCN or DMF at room temperature yielded two regioisomeric tricyclic 1:l adducts, the azacyclols 11/12 and 16/17, respectively (Schemes 3 and 4 ) . The structure of 12 was established by X-ray cryst
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