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Fluorinated 1,3-diketones as reaction intermediates for synthesis of biologically active heterocycles

✍ Scribed by Vijai N. Pathak; Vineeta Sareen; Krishna C. Joshi

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
36 KB
Volume
29
Category
Article
ISSN
0022-1139

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The reactiom of enamina (la-b, 4, 6 ) with fluorinated acyl chlorida (2.4) produced fluorinated 1,3-diketona (3a-O and 1,3-keto-aldehyda (7a-c) in good yieldr M well M byproductr fluorinated acykmida ((k-c). It ir pro& that the resctionm involve nuckophilic attack by the Catom and/or N-atom of the e