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Fluorimetric determination of hydrazine in isoniazid formulations with 2-hydroxy-1-naphthaldehyde

✍ Scribed by J. Mañes; M.J. Gimeno; J.C. Moltó; G. Font


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
312 KB
Volume
6
Category
Article
ISSN
0731-7085

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Liquid chromatographic determination of
✍ J. Mañes; J. Mari; R. Garcia; G. Font 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 206 KB

A selective and sensitive high-performance liquid chromatographic method is described for determination of hydralazine and its metabolites in human plasma. The method involves pre-column derivatization with 2-hydroxy-1-naphthaldehyde at pH 1.2. The reaction product and Methyl Red used as internal st