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Fluoride ion catalyzed aldol reaction between enol silyl ethers and carbonyl compounds

✍ Scribed by Noyori, R.; Yokoyama, K.; Sakata, J.; Kuwajima, Isao; Nakamura, Eiichi; Shimizu, Makoto


Book ID
126092505
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
380 KB
Volume
99
Category
Article
ISSN
0002-7863

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Water-promoted organic reactions. aldol
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As a consequence of the hydrophobic effect, the reaction between silyl enol ethers and aldehydes are shown to proceed without a catalyst in aqueous solution and neutral conditions providing crossed-aldol products with a 2Y~ selectivity, as under pressure, that is the reverse in comparison with the a