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Fluorescent probe for monosaccharides based on a functionalized boron-dipyrromethene with a boronic acid group

✍ Scribed by Nicolas DiCesare; Joseph R Lakowicz

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
106 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new highly fluorescent probe based on a boron-dipyrromethene functionalized with a phenylboronic acid group was synthesized from 2,4-dimethylpyrrol and 4-formylphenylboronic acid. Spectral changes in both absorption and emission spectra were observed in the presence of sugars.

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Boronic acid substituted viologen based
Boronic acid substituted viologen based optical sugar sensors: modulated quenching with viologen as a method for monosaccharide detection
✍ Jason N Camara; Jeff T Suri; Frank E Cappuccio; Ritchie A Wessling; Bakthan Sing πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 83 KB

In our search for an optical glucose sensor we have found that the combination of pyranine 1 and a boronic acid substituted benzyl viologen (o-BBV, 2) signals monosaccharides in the range of 0-1800 mg/dL. The quenching ability of o-BBV is modulated upon sugar binding, which in turn alters the fluore