Fluorescent pattern of apparently normal chromosomes in Burkitt lymphomas
✍ Scribed by George Manolov; Yanka Manolova; Albert Levan; Georg Klein
- Book ID
- 114808115
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 406 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0018-0661
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## Abstract Flow karyotype analysis was performed to assess the feasibility of fluorescence‐activated sorting of Burkitt lymphoma (BL)‐associated translocation chromosomes. The typical 14q+ chromosome in the t(8;14) and the two “variant translations”, the 2q+ in the t(2;8) and the small 22q‐ in the
## Abstract Using a high‐resolution chromosome banding technique, which provided more elongated and distinctly banded chromosomes, some new evidence was obtained for localization of break points in Burkitt lymphoma marker chromosomes. As a result, the characteristic translocation between chromosome
Clonal abnormalities of the long arm of chromosome 13 were detected in 9 of 54 patients with Burkitt lymphoma-leukemia. All abnormalities involved band 13q34, in three patients as t(1;13). The 13q34 abnormalities are thus the second most frequent secondary chromosomal abnormalities, after those of c