Fluorescence in situ hybridization assessment of the telomeric regions of jumping translocations in a case of aggressive B-cell non-Hodgkin lymphoma
β Scribed by Brian A. Gray; Angela Bent-Williams; Julie Wadsworth; Russell L. Maiese; Andres Bhatia; Robert T. Zori
- Book ID
- 114136205
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 626 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0165-4608
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Deletions of the long arm of chromosome 6 (6q) are among the most frequent chromosome aberrations in malignant lymphomas and often occur as secondary changes in addition to typical translocations, such as t(14;18). Using fluorescence in situ hybridization (FISH) with two YAC probes hybridizing to 6q
## Abstract Sixty consecutive evaluable specimens from patients with nonβHodgkin's lymphoma (NHL) were studied for the incidence of polysomy of chromosome 12 by fluorescence in situ hybridization (FISH) with probes for the repetitive DNA sequence in the centromeric region of chromosome 12. Thirtyβs