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Fluorescence determination of 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil in blood serum by high-performance liquid chromatography

โœ Scribed by Masaki Iwamoto; Shigeru Yoshida; Shingo Hirose

Book ID
107996449
Publisher
Elsevier Science
Year
1984
Weight
511 KB
Volume
310
Category
Article
ISSN
0378-4347

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High-pressure liquid chromatographic det
High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur
โœ Teruyoshi Marunaka; Yukihiko Umeno; Kozo Yoshida; Masahiro Nagamachi; Yoshinori ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 591 KB

Oral adminstration of uracil plus ftorafur [ 1-(tetrahydro-2-furanyl)-5-fluorouracil] has a greater antitumor effect than that of ftorafur alone. A high-pressure liquid chromatographic method was developed for the determination of ftorafur in plasma and visceral tissues with a sensitivity of 0.025 l