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Fluid Shear Stress Induces Synthesis and Nuclear Localization of c-fos in Cultured Human Endothelial Cells

✍ Scribed by V. Ranjan; S.L. Diamond

Book ID
115573593
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
379 KB
Volume
196
Category
Article
ISSN
0006-291X

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The c-fos protein belongs to a family of transcriptional cofactors that can complex with proteins of the Jun family and activate mRNA transcription from gene promoters containing an activator protein 1 (AP-1) binding element. The shear stress inducibility of the c-fos protein was studied in human an