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Flow-injection spectrophotometric determination of salbutamol with 4-aminoantipyrine

✍ Scribed by Isabel Dol; Moisés Knochen

Book ID
116900678
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
87 KB
Volume
64
Category
Article
ISSN
0039-9140

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Salbutamol can be determined spectrophotometrically at 605 nm after flow-injection extraction into chloroform after oxidative coupling with 4-amino-N,N-dimethylaniline. The carrier stream is distilled water and the reagents streams contain 5% (w/v) sodium hydrogencarbonate, 0.5% (w/v) potassium hex

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In the proposed procedure, the determination of salbutamol with Folin-Ciocalteau reagent (FC) using a flow injection analysis technique (FIA) with spectrophotometric detection at 750 nm is described. The lab-made FIA system consisted of a peristaltic pump Gilson Minipulse 3 equipped with Tygon tubes