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Flexible Synthesis of Enantiomerically Pure 2,8-Dialkyl-1,7-dioxaspiro[5.5]undecanes and 2,7-Dialkyl-1,6-dioxaspiro[4.5]decanes from Propargylic and Homopropargylic Alcohols

โœ Scribed by Schwartz, Brett D.; Hayes, Patricia Y.; Kitching, William; De Voss, James J.


Book ID
127374678
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
299 KB
Volume
70
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Synthesis of 2,8-Di
โœ Jun Kato; Atsushi Seo; Kazuki Kiso; Kazuaki Kudo; Shinsaku Shiraishi ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

Synthesis of 2,8-Dioxaspiro[4.5]decane-1,3,7,9-tetrone and the Reactions with Amines. -Title compound (VI) is prepared in connection with studies on the highly-sophisticated utilization of itaconic anhydride (I). Ratio of key intermediate (III) to the meta-isomer (IV) is about 4:1. Reaction of (VI)