โ Scribed by Jun Kato; Atsushi Seo; Kazuki Kiso; Kazuaki Kudo; Shinsaku Shiraishi
No coin nor oath required. For personal study only.
Synthesis of 2,8-Dioxaspiro[4.5]decane-1,3,7,9-tetrone and the Reactions with Amines.
-Title compound (VI) is prepared in connection with studies on the highly-sophisticated utilization of itaconic anhydride (I). Ratio of key intermediate (III) to the meta-isomer (IV) is about 4:1. Reaction of (VI) with amines provides diimides (VIII) or imides (X) depending on the hydrocarbon moiety of the amines used. -(KATO, JUN; SEO, ATSUSHI;
๐ SIMILAR VOLUMES
In order to prepare new tacrine-like compounds, the title compounds (VII), (X) and (XV) are synthesized. The synthetic pathway to (VII) represents a shorter and more suitable approach to prepare tacrine metabolites. An alternative route from (VIb) to compound (VIII), which exhibits very strong DNA b
rings with 7 or more members rings with 7 or more members Q 0050 ## 38 -092 Reaction of 2,2-Dibromotricyclo[7.1.0 1,9 .0 1,3 ]decane with Methyllithium: Synthesis of Bicyclo[7.1.0]decadiene-1,2 and Dibromotriangulane Rearrangement. -The reaction of previously unknown dibromide (III) with methylli