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Flexible Low-Intensity Combination Chemotherapy for Elderly Patients with Acute Myeloid Leukemia

✍ Scribed by Arumugam Manoharan; Annette Trickett; Yiu Lam Kwan; Timothy Brighton


Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
188 KB
Volume
75
Category
Article
ISSN
0925-5710

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Eighteen patients aged 60-84 years with acute myeloid leukemia were treated with lowdose combination chemotherapy comprising cytarabine, etoposide, and mitozantrone or 6-thioguanine; seven of these patients had a pre-existing myelodysplastic syndrome. Nine patients achieved a complete remission, and

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The authors developed a therapeutic regimen in which 33 patients aged I I to 61 years (mean 2 SE, 35.9 t 2.3 years) with acute myeloid leukemia (AML) were given intensive induction chemotherapy with Adriamycin (doxorubicin) (ADM), vincristine (VCR) and cytosine arabinoside (ARA-C). Twenty-nine of th