Flexibility of the pyrrolidine ring in proline peptides
β Scribed by Vincent Madison
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1979
- Tongue
- English
- Weight
- 34 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0006-3525
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π SIMILAR VOLUMES
## Abstract The collisionβinduced dissociation (CID) fragmentation reactions of a variety of deprotonated peptides containing proline have been studied in detail using MS^2^ and MS^3^ experiments, deuterium labelling and accurate mass measurements when necessary. The [Mο£ΏHο£ΏCO~2~]^β^ (a~2~) ion deriv
Specificity studies of the enzymatic hydrolysis of proline-containing peptides give further evidence of the unique nature of the Xaa-Pro bond and indicate its role in the limited proteolysis as a structural element protecting the N-terminal chain end. A sensitive, highly specific fluorogenic assay w