Flavonoid glycosides fromPrunus armeniacaand the antibacterial activity of a crude extract

✍ Scribed by Fahima Rashid; Rehana Ahmed; Azhar Mahmood; Zaheer Ahmad; Nazia Bibi; Shahana Urooj Kazmi

• Book ID: 105678879
• Publisher: Springer
• Year: 2007
• Tongue: English
• Weight: 491 KB
• Volume: 30
• Category: Article
• ISSN: 0253-6269
• DOI: 10.1007/bf02993959

✦ Synopsis

Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4',5,7-trihydroxy flavone-7-O-[beta-D-mannopyranosyl (1'''-->2")]-beta-D-allopyranoside (1) and 3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone 3-O-[alpha-L-rhamnopyranosyl (1'''-->6")]-beta-D-galactopyranoside (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments.