## Abstract The interactions of the ribonucleotide poly C with __cis__β and __trans__βdiamminedichloroplatinum (II) were probed with Raman spectroscopy. Both platinum compounds attack the __N__β1 position of the cytosine residue, while the __trans__ form appears to attack the PO~2~^β^ as well. Rama
Flavonoid compounds: a review of anticancer properties and interactions with cis-diamminedichloroplatinum(II)
β Scribed by Beata Kosmider; Regina Osiecka
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 139 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The cytotoxicity of the topoisomerase-I inhibitors, camptothecin and topotecan, toward the SCC-25 human head-andneck squamous-carcinoma cells and the SCC-25/CDDP sub-line made resistant to cis-diamminedichloroplatinum(ll) was assessed alone and in combination with radiation. Topotecan was less cytot
To enhance the therapeutic effect of conventional TRC using intra-arterial (i.a.) DDP plus simultaneous i.v. STS, we combined the AT-11-induced hypertension method with TRC and evaluated its efficacy for a rat uterine tumor, using the simulation of intra-arterial chemotherapy for human uterine tumor
Fourteen patients with advanced head and neck carcinomas received a monthly intravenous regimen of Adriamycin, 40 mg/m2, day 1; cyclophosphamide, 400 mg/m2, day 3; and cis-diamminedichloroplatinum, 20 mg/m2/1 hour, days 1-3 (CAP-3). A regression rate of only 7% (0112 squamous cell carcinomas; 112 ad