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Fisetin, a Dietary Flavonoid, Induces Cell Cycle Arrest and Apoptosis through Activation of p53 and Inhibition of NF-Kappa B Pathways in Bladder Cancer Cells

✍ Scribed by Jing Li; Yongyi Cheng; Weixing Qu; Yi Sun; Zhiping Wang; Hanzhang Wang; Binqiang Tian


Book ID
111316856
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
655 KB
Volume
108
Category
Article
ISSN
1742-7835

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## Abstract This study is the first to investigate the anticancer effect of 6‐dehydrogingerdione (DGE), an active constituent of dietary ginger, in human breast cancer MDA‐MB‐231 and MCF‐7 cells. DGE exhibited effective cell growth inhibition by inducing cancer cells to undergo G2/M phase arrest an