First total synthesis of the antitumor antibiotic (±)-resorthiomycin
✍ Scribed by Datta E. Ponde; S. Ramalingam; Mahesh L. Patil; Hanumant B. Borate; Vishnu H. Deshpande
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 104 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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The first total synthesis of thiobutacin, a butanoic acid with antifungal activity recently isolated from the culture broth of a soil actinomycete, Lechevalieria aerocolonigenes strain VK-A9, is described. The five-step procedure involves readily available and cheap starting materials and can easily
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