First Total Synthesis of Protoapigenone and Its Analogues as Potent Cytotoxic Agents
โ Scribed by Lin, An-Shen; Nakagawa-Goto, Kyoko; Chang, Fang-Rong; Yu, Donglei; Morris-Natschke, Susan L.; Wu, Chin-Chung; Chen, Shu-Li; Wu, Yang-Chang; Lee, Kuo-Hsiung
- Book ID
- 117995651
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 182 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A highly convergent route for assembling bisebromoamide, its stereoisomers and a simplified analogue has been accomplished, which features connecting its left part and right part via thiazoline ring formation at the final stage. Preliminary biological studies revealed that compounds with both propos
A series of curcumin analogues with different substituents at the 4-position of the phenyl group were synthesized and screened for in vitro cytotoxicity against a panel of human cancer cell lines. Several novel curcumin analogues, especially 32 and 34, exhibited selective and potent cytotoxic activi