First total synthesis and absolute configuration of marine cembrane diterpenoid (+)-11,12-epoxysarcophytol A
โ Scribed by Jiong Lan; Zuosheng Liu; Hao Yuan; Lizeng Peng; Wei-Dong Z Li; Ying Li; Yulin Li; Albert S.C Chan
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 109 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
1), an epoxy cembrane diterpenoid from marine soft coral Lobophytum, is described, which allows the assignment of an absolute configuration (11S,12S) of the epoxide function unambiguously.
๐ SIMILAR VOLUMES
Total synthesis of marine bisnor-diterpenoid elisabethin C was successfully carried out by stereoselective construction of bicyclo[4.3.0]nonane ring system with Dieckmann cyclization as the key step. The absolute configuration of elisabethin C was determined based on this total synthesis.
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