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First synthesis of blastidic acid, a component amino acid in an antibiotic, blasticidin S

✍ Scribed by Shinya Nomoto; Akira Shimoyama

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
88 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

Blastidic acid, a component amino acid in an antibiotic, blasticidin S, was synthesized for the first time from a,g-diaminobutyric acid. The synthesis was achieved through elongation of the carbon chain of the starting amino acid, and N-methylation and amidination of an v-amino group.

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ChemInform Abstract: First Synthesis of
ChemInform Abstract: First Synthesis of Blastidic Acid, a Component Amino Acid in an Antibiotic, Blasticidin S.
✍ Shinya Nomoto; Akira Shimoyama πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 23 KB πŸ‘ 2 views

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