Nephrotoxic potential of first-, second-
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Constantin Cojocel; Ulrich GΓΆttsche; Karl-Ludwig TΓΆlle; Karl Baumann
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Article
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1988
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Springer-Verlag
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English
β 697 KB
First-, second-, and third-generation cephalosporins were investigated for their peroidative and nephrotoxic potential. Renal cortical slices from male Wistar rats were incubated at 37 C for 1 h in a phosphate-buffered medium containing the cephalosporin (1.25, 2.5, 5 or 10 mg/ml). In another series