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COMPARATIVE IN VITRO ACTIVITY OF FIRST, SECOND AND THIRD GENERATION CEPHALOSPORINS

✍ Scribed by FORSGREN, ARNE


Book ID
114821573
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
378 KB
Volume
89B
Category
Article
ISSN
0304-131X

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Nephrotoxic potential of first-, second-
✍ Constantin Cojocel; Ulrich GΓΆttsche; Karl-Ludwig TΓΆlle; Karl Baumann πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 697 KB

First-, second-, and third-generation cephalosporins were investigated for their peroidative and nephrotoxic potential. Renal cortical slices from male Wistar rats were incubated at 37 C for 1 h in a phosphate-buffered medium containing the cephalosporin (1.25, 2.5, 5 or 10 mg/ml). In another series