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First metallation of iodo diazines. Iodo and nitrogen directed metallations. Diazines XXII

✍ Scribed by Nelly Plé; Alain Turck; Arnault Heynderickx; Guy Quéguiner


Book ID
104208722
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
578 KB
Volume
54
Category
Article
ISSN
0040-4020

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## Abstract The regioselectivity of the metalation of 2‐chloro‐6‐methoxypyrazine, 2‐fluoro‐6‐methoxypyrazine and 3‐fluoro‐6‐chloropyridazine was studied; the relative __ortho__‐directing power was F > OMe > Cl.