First heterogeneously palladium-catalysed fully selective C3-arylation of free NH-indoles
β Scribed by Giuseppe Cusati; Laurent Djakovitch
- Book ID
- 108284891
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 114 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A new eco-efficient and environmentally friendly palladium/copper catalytic procedure for the C3alkenylation of free NH-indoles is reported. Using homogeneous or heterogeneous heterobimetallic [Pd/ Cu]-catalysts under mild reaction conditions (10 mol% Pd-catalyst and 10 mol% Cu-catalyst, 70 8C, air)
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## Abstract A heterogeneous tetrakis(ammine)palladiumβNaY zeolite {[Pd(NH~3~)~4~]/NaY} catalyst was applied successfully to the Heck arylation of acrolein diethyl acetal using a large variety of aryl and heteroaryl bromides. Depending on the reaction conditions (Heck __versus__ Cacchi) good to high