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First example of the solvent effect on absolute conformation of chiral 3,3-disubstituted 1,4-benzodiazepin-2-ones

✍ Scribed by Amir Avdagić; Andreja Lesac; Vitomir Šunjić


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
479 KB
Volume
55
Category
Article
ISSN
0040-4020

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✍ Lakshmy Ravishankar; Dinesh N. Rele; Kunnavakam V. Geetha; Hari H. Mathur; Giris 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 444 KB

Condensation of substituted cyclohexanones with cinnamaldehydes and morpholine in the presence of anhydrous cerium(II1) chloride was carried out. The stereochemistry of the condensed products, variously substituted 2morpholino-4-phenylbicyclo[3.3.l]nonan-9-ones, was deduced by using the 'H NMR COSY