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Enantioseparation, absolute configuration determination, and anticonvulsant activity of (±)-1-(4-aminophenyl)-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-one

✍ Scribed by Maria Luisa Calabrò; Daniela Raneri; Paola Ficarra; Guido Ferreri; Giovambattista De Sarro; Giuseppe Bruno; Maria Zappalà; Nicola Micale; Silvana Grasso


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
121 KB
Volume
19
Category
Article
ISSN
0899-0042

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Synthesis and anticonvulsant activities
✍ Charles Y. Fiakpui; Oludotun A. Phillips; K. S. Keshava Murthy; Edward E. Knaus 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 305 KB

## Abstract A group of 5‐(2‐chlorophenyl)‐10‐(substituted)‐7__H__‐pyrido[4,3‐__f__][1,2,4]triazolo[4,3‐__a__][1,4]diazepines 7a‐c were synthesized by the acid catalyzed reaction of 5‐(2‐chlorophenyl)‐2‐hydrazino‐3__H__‐pyrido[3,4‐__e__]‐[1,4]diazepine (6) with either trimethyl orthoformate, triethy