Data were analyzed from 419 Fanconi anemia (FA) patients enrolled in the American Registry of the International Fanconi Anemia Registry (IFAR) to determine whether Fanconi anemia (FA) patients without major congenital malformations (CM) have distinguishing characteristics that can lead to an earlier
First announcement of the Fanconi anemia International Registry
โ Scribed by Arleen D. Auerbach; Traute M. Schroeder
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 40 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0340-6717
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Fanconi anemia (FA) is a genetically heterogeneous autosomal recessive syndrome associated with chromosomal instability, hypersensitivity to DNA cross-linking agents, and predisposition to malignancy. The gene for FA complementation group G (FANCG) was the third FA gene to be cloned, and was found t
## Communicated by Marc S. Greenblatt Fanconi anemia (FA) is an autosomal recessive disorder that is defined by cellular hypersensitivity to DNA cross-linking agents, and is characterized clinically by developmental abnormalities, progressive bone-marrow failure, and predisposition to leukemia and