Fanconi anemia (FA) is a genetically heterogeneous autosomal recessive syndrome associated with chromosomal instability, hypersensitivity to DNA cross-linking agents, and predisposition to malignancy. The gene for FA complementation group G (FANCG) was the third FA gene to be cloned, and was found t
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Spectrum of sequence variation in the FANCG gene: An International Fanconi Anemia Registry (IFAR) study
โ Scribed by Arleen D. Auerbach; Jason Greenbaum; Kanan Pujara; Sat Dev Batish; Marco A. Bitencourt; Indira Kokemohr; Hildegard Schneider; Stephan Lobitz; Ricardo Pasquini; Philip F. Giampietro; Helmut Hanenberg; Orna Levran
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 54 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1059-7794
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## Communicated by Marc S. Greenblatt Fanconi anemia (FA) is an autosomal recessive disorder that is defined by cellular hypersensitivity to DNA cross-linking agents, and is characterized clinically by developmental abnormalities, progressive bone-marrow failure, and predisposition to leukemia and