𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Finnish mutations in Swedish HNPCC families

✍ Scribed by Tannergård, Pia; Nordenskjöld, Magnus; Lindblom, Annika


Book ID
109932101
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
131 KB
Volume
1
Category
Article
ISSN
1078-8956

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Germline hMSH2and hMLH1 gene mutations i
✍ Qing Wang; Françoise Desseigne; Christine Lasset; Jean-Christophe Saurin; Claudi 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 145 KB 👁 2 views

Hereditary non-polyposis colon cancer (HNPCC) is a common hereditary disease characterized by a predisposition to an early onset of colorectal cancer. The majority of the HNPCC families carry germline mutations of either hMSH2 or hMLH1 genes, whereas germline mutations of hPMS1 and hPMS2 genes have

PMS2 mutations in HNPCC
✍ BE Hayward; M De Vos; E Sheridan; DT Bonthron 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 67 KB
Ten novel MSH2 and MLH1 germline mutatio
✍ Stefan Krüger; Andrea Bier; Jens Plaschke; Ruth Höhl; Daniela E. Aust; Friedmar 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 65 KB 👁 1 views

Hereditary nonpolyposis colorectal cancer (HNPCC) is one of the most common hereditary cancer-susceptibility syndromes. Germline mutations in mismatch repair genes are associated with the clinical phenotype of HNPCC. We report ten novel germline mutations, three in MSH2 and seven in MLH1. All but on

Novel MLH1 and MSH2 germline mutations i
✍ Zdena Bartosova; Ivana Fridrichova; Maria Bujalkova; Brigitte Wolf; Denisa Ilenc 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 37 KB 👁 1 views

Hereditary nonpolyposis colorectal cancer (HNPCC) is a dominantly-inherited cancer predisposition syndrome, in which the susceptibility to cancer of the colon, endometrium and ovary is linked to germline mutations in DNA mismatch repair (MMR) genes. We have recently initiated a cancer prevention pro