Fine-needle aspiration cytology of sinus histiocytosis with massive lymphadenopathy: A case report
β Scribed by Keyuri D. Patel; Jyoti D. Rege; Leena P. Naik
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 534 KB
- Volume
- 15
- Category
- Article
- ISSN
- 8755-1039
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β¦ Synopsis
Cytological findings of sinus histiocytosis with massive lymphadenopathy (SHML), involving bilateral cervical lymph nodes of a 12-yr-old boy, are presented here. A striking feature was the presence of large histiocytes with abundant pale cytoplasm containing well-preserved lymphocytes, plasma cells, and occasional neutrophils, scattered in a background of reactive lymphoid cells. Subsequent open biopsy of the bmph node mass confirmed the cytologic findings. Cytologic features of SHML are virtually diagnostic and can negate the need for an open biopsy in most cases.
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## Abstract Sinus histiocytosis with massive lymphadenopathy (RosaiβDorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. We report four cases of this disease retrieved from the archives of cytopathology laboratory, BPKIHS, Dharan, Nepal, during the
Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare entity characterized by the prolifration of cells belonging to the macrophage-histiocyte family, but whose exact origin is unknown. A case of SHML occurring in a 62-yr-old female is described in which the diagnosis is initially sugges