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Fine mapping of X-linked clasped thumb and mental retardation (MASA syndrome) in Xq28

✍ Scribed by E. Legius; L. Kaepernick; J. V. Higgins; T. W. Glover


Book ID
115091505
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
330 KB
Volume
45
Category
Article
ISSN
0009-9163

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W e report on a family in which nonsyndromal mild to moderate mental retardation segregates as an X-linked trait (MRX41). T w o point linkage analysis demonstrated linkage between the disorder and marker DXS3 in Xq21.33 with a lod score of 2.56 at 0 = 0.0 and marker DXSllO8 in Xq28 with a lod score