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Fine mapping of the muscular dystrophy (AM) gene on chicken chromosome 2q

✍ Scribed by K. Yoshizawa; K. Inaba; H. Mannen; T. Kikuchi; M. Mizutani; S. Tsuji

Book ID
108633071
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
66 KB
Volume
35
Category
Article
ISSN
0268-9146

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A chicken linkage map, constructed with the Kobe University (KU) resource family, was used to locate the genetic locus for muscular dystrophy of abnormal muscle type (__AM__). The KU resource family is a backcross pedigree with 55 offspring produced from the mating of a White Leghorn F‐line (WL‐F) m

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Facioscapulohumeral muscular dystrophy (FSHD) is a relatively common autosomal dominant neuromuscular disorder. The gene for FSHD has recently been assigned to chromosome 4q35. Although abnormal mitochondrial and biochemical changes have been observed in FSHD, the molecular defect is unknown. In add