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Mapping the facioscapulohumeral muscular dystrophy gene is complicated by chromosome 4q35 recombination events

โœ Scribed by Tawil, R.; Jacobsen, S.J.; Gilbert, J.; Wijmenga, C.; Mendell, J.R.; Winokur, S.; Altherr, M.R.; Weiffenbach, B.; Dubois, J.; Storvick, D.


Book ID
109916203
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
607 KB
Volume
4
Category
Article
ISSN
1061-4036

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A 3.3-kb Kpnl repeat unit within the tandem repeat locus (D4Z4) and its upstream 2.5-kb HinclllKpnl fragment of the facioscapulohumeral muscular dystrophy (FSHD) gene region at 4q35-qter were sequenced and characterized. The 3.3-kb Kpnl unit was 3303 bp in length and contained two homeodomain sequen