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FINASTERIDE INDUCES HYPOXIA-INDUCIBLE FACTOR 1-ALPHA IN THE PROSTATE OF SPRAGUE-DAWLEY RATS

✍ Scribed by Srivastava, Janmejai K; Shukla, Sanjeev; Kamel, Cherry; MacLennan, Gregory T; Seftel, Allen D; Gupta, Sanjay


Book ID
121916877
Publisher
Lippincott Williams and Wilkins
Year
2009
Tongue
English
Weight
46 KB
Volume
181
Category
Article
ISSN
0022-5347

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## Abstract ## BACKGROUND Hypoxia occurs in association with cancer development, the result being a more aggressive and metastatic cancer phenotype. Hypoxia, which activates hypoxia‐inducible factor‐1 alpha (HIF‐1Ξ±), is associated with a number of cellular changes including increased apoptotic res