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Fibroblast Growth Factors and Their Receptors in Urological Cancers: Basic Research and Clinical Implications

✍ Scribed by M.V Cronauer; W.A Schulz; H.-H Seifert; R Ackermann; M Burchardt


Book ID
114218554
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
273 KB
Volume
43
Category
Article
ISSN
0302-2838

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Growth factors (GFs) are a class of proteins that bind to specific cell surface receptors (GF-Rs), inducing a variety of responses including mitosis, in susceptible target cells. Abnormal production, expression, and/or function of GFs or GF-Rs can result in unregulated growth, the hallmark of malign