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Fibroblast growth factor receptor 3 kinase domain mutation increases cortical progenitor proliferation via mitogen-activated protein kinase activation

โœ Scribed by Rachel E. Thomson; Francesca Pellicano; Tomoko Iwata


Book ID
111179913
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
1017 KB
Volume
0
Category
Article
ISSN
0022-3042

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โœ Kunlin Jin; Xiao Ou Mao; Gabriel Del Rio Guerra; Lan Jin; David A. Greenberg ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 306 KB

Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) stimulates cell proliferation in the adult mammalian brain, but the mechanism involved is unknown. To address this issue we treated mouse brain cerebral cortical cultures enriched in neuronal precursors with full-length HB-EGF