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Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

✍ Scribed by Arai, Yasuhito; Totoki, Yasushi; Hosoda, Fumie; Shirota, Tomoki; Hama, Natsuko; Nakamura, Hiromi; Ojima, Hidenori; Furuta, Koh; Shimada, Kazuaki; Okusaka, Takuji; Kosuge, Tomoo; Shibata, Tatsuhiro

Book ID: 121528118
Publisher: John Wiley and Sons
Year: 2014
Tongue: English
Weight: 848 KB
Volume: 59
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.26890

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## 10 -112 1-Oxo-3-aryl-1H-indene-2-carboxylic Acid Derivatives as Selective Inhibitors of Fibroblast Growth Factor Receptor-1 Tyrosine Kinase. -Various title compounds of type (IV) and (V), are prepared for SAR studies to evaluate their inhibition activity on tyrosine kinase. An optimal substitut