𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fibroblast growth factor 7 inhibits cholesterol 7α-hydroxylase gene expression in hepatocytes

✍ Scribed by Zhichao Sun; Xuemei Yu; Weibin Wu; Dongwei Jia; Yinle Chen; Lingling Ji; Xijun Liu; Xiaomin Peng; Yintao Li; Lili Yang; Yuanyuan Ruan; Jianxin Gu; Shifang Ren; Songwen Zhang

Book ID
116303609
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
677 KB
Volume
423
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Bile acids activate fibroblast growth fa
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression
✍ Kwang-Hoon Song; Tiangang Li; Erika Owsley; Stephen Strom; John Y. L. Chiang 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 685 KB

Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced intestinal factors that mediate bile acid feedback inhibition of cholesterol 7␣-hydroxylase gene (C YP7A1) transcription in mouse liver. The mechanism underlying FGF15/FGF19 inhibition of

Hepatocyte growth factor signaling pathw
Hepatocyte growth factor signaling pathway inhibits cholesterol 7α-hydroxylase and bile acid synthesis in human hepatocytes
✍ Kwang-Hoon Song; Ewa Ellis; Stephen Strom; John Y.L. Chiang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 748 KB

Bile acid synthesis in the liver is regulated by the rate-limiting enzyme cholesterol 7␣-hydroxylase (CYP7A1). Transcription of the CYP7A1 gene is inhibited by bile acids and cytokines. The rate of bile acid synthesis is reduced immediately after partial hepatectomy and during the early stage of liv

Glucagon and cAMP inhibit cholesterol 7α
Glucagon and cAMP inhibit cholesterol 7α-hydroxylase (CYP7a1) gene expression in human hepatocytes: Discordant regulation of bile acid synthesis and gluconeogenesis
✍ Kwang-Hoon Song; John Y. L. Chiang 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 478 KB

The gene encoding cholesterol 7␣-hydroxylase (CYP7A1) is tightly regulated to control bile acid synthesis and maintain lipid homeostasis. Recent studies in mice suggest that bile acid synthesis is regulated by the fasted-to-fed cycle, and fasting induces CYP7A1 gene expression in parallel to the ind