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Fibroblast growth factor 23 and calcium phosphate homeostasis after pediatric renal transplantation

✍ Scribed by Michael van Husen; Anja Lehnhardt; Ann-Katrin Fischer; Florian Brinkert; Sebastian Loos; Jun Oh; Markus J. Kemper


Book ID
115100147
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
169 KB
Volume
16
Category
Article
ISSN
1397-3142

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In X-linked hypophosphatemia (XLH) and in its murine homologue, the Hyp mouse, increased circulating concentrations of fibroblast growth factor 23 (FGF-23) are critical to the pathogenesis of disordered metabolism of phosphate (P(i)) and 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. In this study, we hypo