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Fiber-Based Liquid-Phase Micro-Extraction of Mebeverine Enantiomers Followed by Chiral High-Performance Liquid Chromatography Analysis and Its Application to Pharmacokinetics Study in Rat Plasma

✍ Scribed by Mehdi Hatami; Khalil Farhadi; Amir Tukmechi


Book ID
112049486
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
241 KB
Volume
24
Category
Article
ISSN
0899-0042

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi