Fever induced by macrophage inflammatory protein-1 (MIP-1) in rats: Hypothalamic sites of action
✍ Scribed by Miñano, F.J.; Sancibrian, M.; Myers, R.D.
- Book ID
- 122603254
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 903 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0361-9230
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The effect of macrophage inflammatory protein-lp (MIP-1P) on body temperature, following its injection into the anterior hypothalamic pre-optic area (AINPOA), was examined by a radiotelemetry system in the freely moving rat. The purpose of this study was to examine the action of an inhibitor of prot
The chemokines, macrophage inflammatory protein-1 (MIP-1) and its subunit MIP-lP, induce an intense fever in the rat when they are injected directly into the anterior hypothalamic, pre-optic area (AH/ POA), a region containing thermosensitive neurons. The purpose of this study was to compare the cen