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Fetal hemoglobin expression in the compound heterozygous state for−117 (G→A) Aγ HPFH and IVS-1 nt 110 (G→A) β+ thalassemia: a case study

✍ Scribed by G. V. Z. Dedoussis; K. Sinopoulou; M. Gyparaki; A. Loutradis


Book ID
114422896
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
110 KB
Volume
65
Category
Article
ISSN
0902-4441

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We studied a family in which two inherited defects of the non-␣-globin cluster segregate: Greek hereditary persistence of fetal hemoglobin (HPFH) and ␤-thalassemia. The compound heterozygote is a healthy man with 43% HbF, G ␥/ A ␥ ratio (27:73) differing from that of 10 simple heterozygotes for the

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