## Fetal Loss in Down Syndrome Pregnancies In a recent paper, Morris et al. (1999) deduce that about 43 per cent of Down syndrome pregnancies are destined to result in spontaneous loss between the first trimester and term. This relatively high estimate for the rate of loss is derived on the basis o
Fetal breasts in normal and down syndrome fetuses
โ Scribed by Petrikovsky, Boris M.; Schneider, Elizabeth P.; Klein, Victor R.; Wyse, Linda J.; Lesser, Martin
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 362 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0091-2751
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โฆ Synopsis
To assess the validity of fetal breast size measurement as a sonographic marker in fetuses with Down syndrome. Methods: Fetal breasts were studied in 26 fetuses with trisomy 21 and 78 fetuses with normal chromosomes. Breasts were identified and measured in a cross-sectional plane of the fetal chest at the level of the four-chamber view of the heart. Normal fetuses had a mean breast size of 3.8 mm * 1.1 mm. Fetuses with Down syndrome had a mean breast size of 1.9 mm ? 0.7 mm ( p s 0.0001). Diminished breast size measured by ultrasound in the second trimester may be helpful in identifying fetuses with Down syndrome. 0 1996 John Wiley & Sons, Inc.
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It is recognized that pregnancies with Down syndrome are liable to end in spontaneous fetal loss. It is important to determine the magnitude of this effect so that it can be taken into account when assessing the results of antenatal screening programmes for Down syndrome. Failure to do so will tend
We determined the type and frequency of abnormal sonographic findings in 187 Down syndrome fetuses. Examinations were performed transvaginally or transabdominally between 9 and 28 weeks' gestation. Consecutive scans performed prior to knowledge of the fetal karyotype (n=144) were analysed separately