We have studied a family in which four members of the same generation were affected with Wiedemann-Beckwith syndrome (WBS). Trisomy llp15 was demonstrated using molecular probes in interphase nuclei of formalin-fixed paraffin-embedded placenta from a stillborn fetus and in peripheral blood lymphocyt
Nonimmune fetal hydrops and down syndrome
β Scribed by Fujimoto, Atsuko ;Broom, Diane L. ;Shinno, Nancy W. ;Wilson, Miriam G. ;Opitz, John M.
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 267 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0148-7299
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We have studied a fetus with the prenatal sonographic diagnosis of severe nonimmune hydrops fetalis at 16 weeks of gestation, who was later shown by amniocentesis to have Down syndrome.
## Fetal Loss in Down Syndrome Pregnancies In a recent paper, Morris et al. (1999) deduce that about 43 per cent of Down syndrome pregnancies are destined to result in spontaneous loss between the first trimester and term. This relatively high estimate for the rate of loss is derived on the basis o
It is recognized that pregnancies with Down syndrome are liable to end in spontaneous fetal loss. It is important to determine the magnitude of this effect so that it can be taken into account when assessing the results of antenatal screening programmes for Down syndrome. Failure to do so will tend