Ferrocene-Assisted Stabilization of Collagen Mimetic Triple Helices: Solid-Phase Synthesis and Structure
β Scribed by Dey, Subrata K.; Kraatz, Heinz-Bernhard
- Book ID
- 126299949
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 283 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1043-1802
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π SIMILAR VOLUMES
The triple-helical conformation of collagen has been proposed to be important for mediation of cellular activities, such as adhesion and activation, extracellular matrix assembly, and enzyme function. We have developed synthetic protocols that allow for the study of biological activities of specific
## Abstract As model peptides of collagen, (ProβProβGly)~__n__~ (__n__ = 10, 12, 14, and 15) and (ProβProβGly)~__n__~(AlaβProβGly)~__m__~(ProβProβGly)~__n__~ (2__n__ + __m__ = 15; __m__ = 1, 3, and 5) were synthesized by the solidβphase method. The final products were pure when checked by highβvolt