Experimental design techniques were used to study the influence of the composition of the culture medium on the production of hepatitis B virus pre-S2 antigen by the methylotrophic yeast Hansenula polymorpha, pH, phosphoric acid, ammonium chloride and yeast extract concentrations were selected as ex
Fermentation study for the production of hepatitis B virus pre-S2 antigen by the methylotrophic yeastHansenula polymorpha
β Scribed by M. R. de Roubin; L. Bastien; S. -H. Shen; D. Groleau
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 872 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1476-5535
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## Abstract Factors influencing and predictive of seroconversion from hepatitis B e antigen (HBeAg) to antibody (antiβHBe) were sought in a caseβcontrol study of 61 patients with chronic hepatitis B who had been observed from 5 years before to 1 year after seroconversion, and 32 patients who did no