## Abstract Over 90% of infants infected with hepatitis B virus (HBV) caused by motherβtoβinfant transmission will evolve to carrier status, and this cannot be prevented until widespread administration of the HB vaccine and hepatitis B immune globulin (HBIG) is implemented. This prospective study o
Female to male transmission of hepatitis b virus between chinese spouses
β Scribed by Dr. Ying-Chin Ko; Yea-Yin Yen; Shu-Mei Yeh; Shou-Jan Lan
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 333 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
Three hundred thirty-seven community-based spouses were tested for the presence of hepatitis B virus (HBV) markers to assess the direction of HBV transmission between couples. The prevalence rate of HBV infection among husbands whose wives were hepatitis B surface antigen (HBsAg)-positive was higher compared with those whose wives were HBsAg-negative. Moreover, the frequency of HBV seropositivity among husbands was 100% if their wives carried HBeAg and showed a trend correlation ( P = .009). The prevalence difference was 13.8%. and the 95% confidence interval (95% CI) was 7.9-19.7% after adjusting for spouses' age. In contrast, HBV infection rate of wives did not show an association with the husbands' HBsAg or HBeAg carrier status. The prevalence difference was 7.1%, but 95% CI was -2 . S l 6 . 8 % after adjusting for spouses' age. Female to male transmission of HBV between spouses appears to be more efficient.
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