Feedback Regulation of the Proliferation of the Undifferentiated Spermatogonia In the Chinese Hamster By the Differentiating Spermatogonia
β Scribed by D. G. de Rooij; D. Lok; D. Weenk
- Book ID
- 114715591
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 622 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0960-7722
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In this study the yield of the proliferation of the differentiating spermatogonia into spermatocytes was determined in five Chinese hamsters. Large differences of up to a factor 2 were found between the numbers of A1 spermatogonia in the various animals. However, the numbers of leptotene spermatocyt
The sequence of centromere separation in spermatogonial chromosomes of untreated and cyclophosphamide-treated Chinese hamsters is described. Centromeres of chromosome 1 and 2 separated much earlier than all other chromosomes, especially 6-8. Cyclophosphamide significantly inhibits the centromere sep
Acute and chronic treatment of Chinese hamsters and mice with 5, 25 and 125 mg/kg isoniazid (INH) given by oral intubation did not enhance the chromosomal aberration frequencies in spermatogonia. The structural and numerical aberration rates remained in the range of spontaneous events even after the