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Feasibility and early results of accelerated radiotherapy for head and neck carcinoma in the elderly

✍ Scribed by Abdelkarim S. Allal; Daphné Maire; Minerva Becker; Pavel Dulguerov

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
73 KB
Volume
88
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

Accelerated radiotherapy (RT) represents a promising method with which to improve the treatment outcome in patients with head and neck carcinoma. However, its applicability to elderly patients has not been well established.

This study assessed treatment toxicities, patient compliance, and oncologic results in patients age Ն 70 years who were treated with an accelerated concomitant boost RT schedule. Between 1991 and 1997, 39 patients aged Ն 70 years (mean, 75 Ϯ 6 years) presenting with carcinomas of the oral cavity, pharynx, or larynx were treated radically with a modified concomitant boost RT schedule (planned dose of 69.9 grays [Gy] over 38 days). Based on American Joint Committee on Cancer staging, there were 14 patients with Stage I-II disease and 25 patients with Stage III-IV disease. Eighty-one patients age Ͻ 70 years who were treated with the same RT schedule served as a comparative group. The median follow-up for the surviving patients was 19 months (range, 3-65 months) and 23 months (range, 2-76 months), respectively, for the elderly and younger patient groups.

METHODS.

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